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The company’s Quantum peristaltic pump uses a patented single-use cartridge technology and is applicable to downstream bioprocessing.
Watson-Marlow Fluid Technology Group (WMFTG) showcased its bioprocessing products at INTERPHEX 2019 in New York, including its Quantum peristaltic pump with patented ReNu single-use (SU) cartridge technology for downstream processing.
Quantum sets the standard for high-pressure feed pumps in SU tangential flow filtration, virus filtration (VF), and ultra-high-performance liquid chromatography, according to the company. The pump represents a step-change in pump technology for bioprocessing by enabling higher downstream process yields throughout the pressure range, delivering virtually pulse-free linear flow, lowest shear, and easy validation aligned with Biophorum Operations Group (BPOG) guidelines, WMFTG states.
Quantum delivers high accuracy with flow linearity independent of back-pressure, which removes the need for flow meters and load cells. The pump also delivers ultra-low shear, half that of diaphragm pumps, a factor that increases product viability to help maximize process yield.
Quantum is being used at Goodwin Biotechnology Inc. (GBI), a US-based, GMP contract development and manufacturing organization, to speed up completion of a purification platform for one of its customers. GBI switched to Quantum after realizing that their existing pump technology could not handle high pressures on ultrafiltration membranes for large volumes that were required. With WMFTG’s pump, GBI is able to concentrate 1500 liters of a product to 100 liters in approximately seven hours.
The ReNu SU cartridge technology used in Quantum offers validation and extractable data in line with BPOG, Bio-Process Systems Alliance, United States Pharmacopeia, and International Organization for Standardization guidelines.
INTERPHEX 2019 was held in New York, NY, at the Javits Convention Center from April 2–4, 2019.
Source: Watson-Marlow Fluid Technology