News|Articles|November 5, 2025

The Scale-up Process: from Analytical to Preparative Scale LC Separations

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Key Takeaways

  • High-yield preparative scale separation is essential for both small and large molecules, particularly in biopharmaceuticals.
  • Optimizing separation techniques ensures the purity of isolated fractions, crucial for product integrity.
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This knowledge note demonstrates how to achieve a high-yield preparative scale separation and confirm the purity of the resulting isolated fractions. Large-scale preparative separations are important not only for small molecules, but also for large molecules with a growing interest in biopharmaceuticals.

This knowledge note demonstrates how to achieve a high-yield preparative scale separation and confirm the purity of the resulting isolated fractions. Large-scale preparative separations are important not only for small molecules, but also for large molecules with a growing interest in biopharmaceuticals.

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