SP Scientific Licenses Praxair's ControLyo Nucleation Technology

October 14, 2010

SP Scientific (Gardiner, NY) has signed a license agreement to use Praxair's (Danbury, CT) ControLyo nucleation-on-demand technology, which provides pharmaceutical and biotechnology companies with control over the freeze-drying process for drug developmental efforts.

SP Scientific (Gardiner, NY) has signed a license agreement to use Praxair's (Danbury, CT) ControLyo nucleation-on-demand technology, which provides pharmaceutical and biotechnology companies with control over the freeze-drying process for drug developmental efforts.

The ControLyo technology was specifically developed to control the freezing step of lyophilization. In traditional lyophilization, the freezing step is uncontrolled because of the random nature of the nucleation or crystal-forming process. The ControLyo technology, however, controls the nucleation temperature to within 1 °C of its freezing point, which improves product uniformity, quality, and yield, and can reduce cycle times by as much as 40%.