Single-Use Systems Offer Lab-to Pilot-Scale TFF Operations

Novasep’s Sius single-use tangential flow filtration skid (TFF) is the first on the market to offer a 100% single-use TFF solution, according to the company.

The Sius TFF skid is comprised of an automated bench top unit with a fully disposable flowpath. It is capable of lab-to pilot-scale TFF operations. The unit accomodates surface areas from 0.1 m2 to 2 m2 for microfiltration and ultrafiltration/diafiltration applications.

Novasep has achieved a 73-80% reduction in consumable price to $800/m², by designing the TangenX Sius single-use TFF cassettes.  The Novasep Sius TFF skid’s flowpath can be combined with TangenX Sius TFF cassettes and filter plate inserts with the option of a feed bag, to provide a single-use TFF solution from a single supplier for pre-clinical to clinical cGMP biomanufacturing. It is also one of the only solutions to enable cGMP validated integrity tests.

Novasep