Merck KGaA and Telix Partner on Pan-Cancer Clinical Combination Studies

Article

Merck KGaA has partnered with Telix Pharmaceuticals to conduct combination clinical studies for cancer therapy.

On Aug. 18, 2021, Telix Pharmaceuticals, an Australian-based radiopharmaceutical company, announced a collaboration with Merck KGaA, Darmstadt, Germany, to conduct clinical combination studies for cancer treatment. The studies will combine one of Merck’s investigational proprietary DNA damage response inhibitor (DDRi) molecules with each of Telix’s molecularly targeted radiation (MTR) therapeutic programs—TLX591 (177Lu-rosopatamab) and TLX250 (177Lu-girentuximab). This collaboration builds on a strategic research collaboration agreement the two companies began in August 2019.

TLX591 and TLX250 are late-stage products in development for prostate and renal cancer therapy, respectively. Under the collaboration and based on encouraging pre-clinical data from their initial research partnership, the two companies have agreed to investigate the synergy of these product assets with Merck’s DDRi compound across a wide variety of oncology indications in the clinic.

“This collaboration represents the vanguard of nuclear medicine and oncology, and we are excited by the level of new data and intellectual property already generated, which is highly supportive of clinical translation. Pre-clinical studies provide evidence that the combined effect of Merck’s DDRi compound with Telix’s MTR candidates has potential to significantly impact cancer by improving efficacy and reducing the required radiation dose for tumor reduction and remission, compared to MTR only,” said Christian Behrenbruch, CEO, Telix, in a company press release.

Source: Telix Pharmaceuticals

Newsletter

Stay at the forefront of biopharmaceutical innovation—subscribe to BioPharm International for expert insights on drug development, manufacturing, compliance, and more.

Recent Videos
Shortcut from point A to point B | Image Credit: © Olivier Le Moal - stock.adobe.com
Behind the Headlines, Episode 21: Waters-BD Merger, Merck’s $10B Bet, and Biotech’s Investment Frontiers
Wooden blocks spelling TARIFFS are placed on a map of North America, specifically over the United States and Mexico | Image Credit: © Rokas - stock.adobe.com
Jason Waite, International Trade Expert, Alston & Bird
DC skyline at night with view of the White House and the Washington Monument | Image Credit: © Jessica - stock.adobe.com
Related Content
© 2025 MJH Life Sciences

All rights reserved.