In Pursuit of High Concentration Protein Formulations

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Webinar Date/Time: Thu, Mar 21, 2024 11:00 AM EDT

Join this webinar to explore the complexities of subcutaneous injections for protein and antibody therapeutics and learn how to navigate molecular challenges to optimize formulation for high concentration solutions.

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Event Overview:

Subcutaneous injection presents many advantages over IV administration. Yet, attaining the required concentrations for such injections proves daunting, particularly for protein and antibody-based therapeutics. Concentrated protein and antibody solutions can become highly viscous, form undesirable high molecular weight aggregates, or precipitate. In this webinar, we critically review the molecular intricacies behind these challenges and propose a systematic exploration of the formulation space to identify excipients conducive to high concentration formulations.

Key Learning Objectives:

  • Delve into the molecular underpinnings of challenges in high concentration formulation development
  • Examine the advantages of systematic, data-driven approaches compared to platform approaches
  • Assess strategies for achieving high concentration protein formulation

Who Should Attend:

  • Directors
  • CMC Professionals
  • Formulation Scientists
  • R&D Scientists


Axel Müller, PhD
Senior Research Scientist III Formulation

Dr. Axel Müller joined Curia in 2021. His team manages a range of formulation projects, from early-stage development to compatibility studies. He earned his PhD in protein X-ray crystallography from the University of York, UK, and researched membrane proteins at Caltech.

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