On July 22, 2025, the Cell and Gene Therapy Catapult (CGT Catapult) announced that it has made its first investment as part of the Cross-Catapult Investment Pilot in a trans-splicing gene therapy platform for liver cancer created by Spliceor, an early-stage R&D company that was spun out of the Department of Medicine at the University of Cambridge, United Kingdom (1). The investment pilot is supported by Innovate, UK and allows organizations involved in the Catapult Network to make seed investments in innovative companies. The pilot works with industry to ensure the development of novel therapies.
Key Takeaways
- The Cross-Catapult Investment Pilot in a trans-splicing gene therapy platform for liver cancer created by Spliceor.
- An investment committee will assess potential future investments in advanced therapies developed in the UK.
- CGT Catapult issues statement about the UK government’s Life Sciences Sector Plan.
A trans-splicing gene therapy for liver cancer treatment
The pilot program’s investment in Spliceor will support the development and validation of the company’s trans-splicing gene therapy platform for cancer and other treatments.
“Spliceor is an innovative advanced therapies company with the potential to develop a life-changing gene therapy to benefit patients,” Matthew Durdy, chief executive of the CGT Catapult, said in a press release (1). “By working with Innovate UK to invest in promising companies, like Spliceor, that have strong technologies and clear applications, we hope to accelerate their growth, boost the advanced therapies ecosystem in the UK, and ultimately lead to more therapies entering clinical trials and commercial use.”
“We are grateful to receive this significant investment, which recognizes Spliceor’s potential to transform lives through innovative gene therapies,” Tim Landy, CEO, Spliceor, added. “This funding will accelerate our research and development, enabling us to build on our goal of delivering more specific and effective gene therapies, advancing our assets toward clinical trials and ultimately delivering life-changing treatments to patients.”
An investment committee will assess potential future investments in advanced therapies developed in the UK.