New Research Reveals a Promising Functional Alternative to Surfactants within Biologic Formulations
-Research suggests cyclodextrins could replace surfactants for biologics.
-Studies on HPßCD indicate it to be a potential alternative to polysorbates
The required advances in pharmaceutical manufacturing occurred when excipient suppliers developed multi-functional types for direct compression. Roquette’s PEARLITOL® Flash, a combination of mannitol and starch, is a ready-to-use excipient for orodispersible tablets. This article describes its application to formulation and how this delivers advantages like robustness and rapid disintegration time. PEARLITOL® Flash means problem-free ODT formulation.