
This case study reviews how quality-by-design principles can be implemented in an intermediate chromatography purification step that uses cation-exchange chromatography.Abstract

This case study reviews how quality-by-design principles can be implemented in an intermediate chromatography purification step that uses cation-exchange chromatography.Abstract

The authors explore the use of statistical experimental design and multivariate analysis to develop a drug substance formulation matrix.

Published: August 1st 2015 | Updated:

Published: November 2nd 2015 | Updated: