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Using LC–MS to Analyze Adeno-Associated Virus Critical Quality Attributes

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Featured Resources for Oligonucleotides Separations

Featured Resources for Glycan Analysis

Fundamentals of Oligonucleotide Separation by HPLC

Preparation of Released N-Glycan Samples from Monoclonal Antibodies Using Agilent AdvanceBio Gly-X 2-AB Express for LC-Fluorescence Analysis

By using optimized reagents and method conditions, learn how to reduce 2-AB labelling of glycans from days to just two hours.

Assessing Multiple Critical Quality Attributes of Monoclonal Antibody and Comparability Assessments

Discover how LC/MS peptide mapping can be used to characterize and quantify different monoclonal antibody (mAb) critical quality attributes (CQAs).

Mass Spectrometric Characterization of Antibody-siRNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q-TOF

Small interfering RNAs (siRNAs) are a promising type of RNA-based therapeutic drugs that demonstrate effectiveness on gene silencing through RNA interference (RNAi).

Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF

Workflow for the characterization of critical quality attributes (CQAs) of intact adeno-associated viruses (AAVs), together with identification of the capsid proteins.

Size Exclusion Chromatography Method Development of NIST mAb Using an Agilent AdvanceBio SEC 200 Å 1.9 μm Column

Learn how to perform method optimization using a bio-inert quaternary LC instrument to screen multiple mobile phase compositions for aggregate analysis of NIST mAb.