TriLink Biotechnologies Introduces CleanCap M6 Analog

TriLink Biotechnologies launched its new cap analog, CleanCap M6, on May 9, 2023, which is expected to help developers and researchers maximize the impact of their messenger RNA (mRNA) therapeutics and vaccines while reducing overall manufacturing costs, according to a company press release. The introduction of CleanCap M6 technology is intended to improve mRNA potency with the highest protein expression of any CleanCap analog to date.

“TriLink’s portfolio of CleanCap mRNA capping technology is expected to be the new go-to capping method in the very near future—it is the future,” said Kate Broderick PhD, chief innovation officer at Maravai LifeSciences, in a press release. “What excites me most about this novel analog is its ability to make mRNA an even more powerful therapeutic than we have seen previously.”

The first CleanCap analog was launched in 2017, and since then, the capping technology has been incorporated in one of the first commercially approved COVID-19 vaccines.

“mRNA is clearly an emerging therapeutic modality where mRNA vaccines and therapeutics are expanding rapidly,” said Drew Burch, EVP of TriLink’s Nucleic Acid Products division, in a press release. “CleanCap M6, and the entire CleanCap portfolio, joins a strong roster of synthesized nucleic acids, NTPs, and more that we expect to continue to grow.”

Source: TriLink Biotechnologies