Small-Batch Aseptic Fill/Finish System

February 2, 2019

BioPharm International

Volume 32, Issue 2

Page Number: 40

The Flexicon FPC60 peristaltic fill/finish system from Watson-Marlow Fluid Technology Group can use a variety of modules that allow users to create their own customized filling solution to suit small-batch applications.

The Flexicon FPC60 peristaltic fill/finish system from Watson-Marlow Fluid Technology Group can use a variety of modules that allow users to create their own customized filling solution to suit small-batch applications. 

The modules include vial infeed, filling, stoppering, capping, auto-reject, gas purging, and product outfeed. The small-footprint system can handle vial sizes between 2R and 100H and has servo-driven auto adjustment, which allows for minimal tools and quicker set-up between batches. When supplied with in-line check weighing, the system offers dynamic prime, no-intervention initial calibration and dynamic recalibration, meaning each vial is confirmed to be within specification.

According to the company, filling is assured from less than 0.2ml up to 100ml. Features include throughput of up to 45 vials per minute, options for automatic segregation of rejects, fluid path developed for single use, horizontally mounted pump head for one-handed interaction, remote operation from outside a cleanroom or distant location, and a SQL server-based data management system. Additionally, the integration of laminar airflow, restricted-access barrier systems, or isolators is also available.

Watson-Marlow Fluid Technology Group

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