Purification Resin Increases Efficiency

Publication
Article
BioPharm InternationalBioPharm International-12-01-2014
Volume 27
Issue 12

Tosoh Bioscience’s CaPure-HA hydroxyapatite chromatography resin is designed for the purification of monoclonal antibodies, polyclonal antibodies, and antibody fragments, and the separation of antibody isoforms and isozymes.

Tosoh Bioscience’s CaPure-HA hydroxyapatite chromatography resin is designed for the purification of monoclonal antibodies, polyclonal antibodies, and antibody fragments, and the separation of antibody isoforms and isozymes. The resin has a pressure rating of 10 MPa, a mean particle size of 39 μm, a pH stability of 6.5-14, and alkaline stablility in 0.5 mol/L NaOH for greater than 50 CIP cycles.


The dynamic binding capacity, at 10% breakthrough, is greater than 20 g/L for lysozyme at residence times as low as one minute, greater than 30 g/L for human lgGs at residence times as low as two minutes, and greater than 50 g/L for human lgGs at residence times of five minutes.

Tosoh Biosciencewww.tosohbioscience.com

 

Newsletter

Stay at the forefront of biopharmaceutical innovation—subscribe to BioPharm International for expert insights on drug development, manufacturing, compliance, and more.

Recent Videos
DC skyline at night with view of the White House and the Washington Monument | Image Credit: © Jessica - stock.adobe.com
Related Content
© 2025 MJH Life Sciences

All rights reserved.