Automated inline dilution system can reduce downstream processing delays.

Automation Eases Bottlenecks

Adoption of single-use technologies prompts need for PAT-friendly sensors.

Single-Use Sensors Increase Process Understanding

Defining a holistic approach to validation and quality assurance for finished drug products.

Prepping Fill/Finish Systems

Creativity and collaboration are required to overcome complex method development challenges.

Process Intensification and PAT for Real-Time Release

Topic

Articles

Sanofi will offer access to its infrastructure and expertise to help BioNTech produce over 125 million doses of its COVID-19 vaccine in Europe.

Sanofi to Help Manufacture and Supply BioNTech’s COVID-19 Vaccine

Cynthia A. Challener, PhD, is a contributing editor to BioPharm International.

Connected, integrated bioprocessing enterprises with greater data analytics capabilities are coming.

Remote Monitoring and Big Data Advance Upstream Automation

Clinical material for a Theratechnologies product in development will be produced at PPS’ manufacturing facility in Lexington, KY.

Piramal Pharma Solutions to Provide Sterile Fill/Finish Support to Theratechnologies

A complicated vaccination rollout and mixed messages may derail the pandemic endgame

A Hopeful but Dangerous Phase

Plasma-based proteins and cell-based therapies have significant potential to address unmet medical needs.

The 40,000-ft.2 facility will feature eight cleanrooms with configurations for the production of cell and viral vector products.

Fujifilm to Establish New Manufacturing and Innovation Center in Massachusetts 

Henogen will be integrated into Thermo Fisher’s Pharma Services business within its Laboratory Products and Services segment.

Thermo Fisher Completes $875-Million Acquisition of Novasep’s Viral Vector Manufacturing Business

The acquisition significantly expands Precision Medicine Group’s cell and gene therapy expertise.

Precision Medicine Group Acquires Project Farma

The 17,000 m2 facility will serve as a process development and manufacturing site for Chinese companies developing medicines as well as multinationals with manufacturing requirements in China.

Cytiva Delivers Chinese Biomanufacturing Facility to Lonza

Acorda’s Chelsea, MA facility will serve as a global center of excellence in the Catalent network for spray-dried dispersion and dry powder encapsulation and packaging.

Catalent to Acquire Acorda Therapeutics’ Manufacturing and Packaging Operations

Baxter will provide commercial-scale manufacturing services at its Halle/Westfalen, Germany facility to prepare Novavax’s COVID-19 vaccine candidate for distribution in the United Kingdom and European markets.

Baxter and Novavax Enter into COVID-19 Vaccine Sterile Manufacturing Agreement

The company plans to expand its global production capacity across six existing manufacturing facilities in Europe and the United States, as well as a new manufacturing facility in the US.

Pall to Invest $114 Million to Expand its Global Production Capacity

The new facility, which will be operated by Fujifilm Diosynth Biotechnologies, will provide large-scale cell-culture manufacturing of bulk drug substance with 8 x 20,000-L bioreactors.

Fujifilm to Invest Over $2 Billion into US Biopharmaceutical Manufacturing Facility  

Intravacc and Cristal Therapeutics have entered into a strategic collaboration for the development of novel vaccine programs against human diseases.

Intravacc, Cristal Therapeutics Collaborate on Novel Vaccine Platforms

Demand for specific advanced laboratory skills creates a positive employment market.

Talent-Driven Market for Laboratory Technicians

Using rDNA technology to synthesize production of proteins and peptide hormones, the biotech startup has achieved synthetic production of insulin, potentially lowering insulin cost by 30%. 

rBIO Hits Key Lab Milestone with Synthetic Production of Insulin

Jennifer Markarian is manufacturing editor of BioPharm International.

Podcasts

BioPharm International interviewed Cloudleaf about trends in tracking vaccines through the supply chain.

Trends in Vaccine Tracking

After a hectic 2020, biopharma looks to deliver on COVID-19 vaccines and move other promising therapies forward.

Biopharma Gets Back to “New Normal” Business

Essential bio/pharma employees show hard work and dedication can pay off, for patients.

Compensation Does Not Necessarily Align with Job Satisfaction

Advances in development, data management, and automation, and closer collaboration with contract development and manufacturing partners,  are pushing more therapies closer to commercialization.







