Therapeutic Potential of Green, Synthesized Gold Nanoparticles

Gold nanoparticles (AuNPs) are important components for biomedical applications and are widely employed for diagnostics and therapeutics. Nanoparticles are mainly synthesized through chemical and physical methods, which are often costly and potentially harmful. Synthesis of nanoparticles using plants, however, is less toxic and more effective. Recently, researchers have been focusing on green synthesis of AuNPs. This study aims to use plant-leaf extract for the green synthesis of AuNPs and to evaluate their antibacterial and antioxidant activity. The results indicated that AuNPs can be synthesized using a simple method with extracts from Adiantum capillus veneris(ACV) and Pteris quadriureta(PQ) leaves. The characterization of the AuNPs was done by ultraviolet-visible spectroscopy, powder X-ray diffraction, Fourier transform infrared spectroscopy, and energy dispersive X-ray spectroscopy. The nanoparticles of ACV and PQ were seen at the wavelength of 573 nm and 520 nm, respectively. The nanoparticles of both ACV and PQ leaves extract showed antioxidant, antibacterial, and antifungal activities. ACV nanoparticles showed increased antioxidant and antimicrobial activity compared to PQ. Taken together, the results reveal that the AuNPs synthesized from leaves of ACV and PQ possesses antioxidant and antimicrobial activity.

Peer-reviewed

Submitted: July 30, 2019
Accepted: Oct. 15, 2019

About the authors

A. Usha Rajananthini, biotechurn@gmail.com, and Satabdi Rautray, rautray.satabdi@gmail.com, are with the Department of Biotechnology, Mother Teresa Women’s University, Kodaikanal, Tamil Nadu, India. 

Correspondence should be addressed to both authors.

Article Details

BioPharm International
Vol. 33, No. 1
January 2020
Pages: 30–38

Citation

When referring to this article, please cite it as S. Rautray et al., “Therapeutic Potential of Green, Synthesized Gold Nanoparticles,” BioPharm International 33 (1) 2020.