Upstream Processing

Feliza Mirasol is the science editor for 

Articles

Advancements in bioprocessing technologies test microbial fermentation adaptability.

Bioprocessing Innovations Pose New Challenges for Fermentation

Corning’s new Ascent fixed bed reactor (FBR) system is an automated bioproduction platform designed to significantly improve yields and reduce bioproduction costs.

Corning’s New Cell and Gene Therapy Platform Demonstrates Large-Scale Bioproduction

Automation is one asset that benefits cell harvesting by cutting out laborious manual steps and minimizing contamination.

Cell Harvesting Sees Benefits from Automated Processes

The companies work to develop and supply advanced cell models that better reflect an in-vivo environment to improve drug discovery accuracy and efficiency.

Lonza to Supply Prequalified Hepatocytes for Use on CN Bio’s Organ-on-a-Chip Range

Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.

Cell-free Expression Systems Pose Cell Culture Alternative

Originally established in the 1970s as a fetal bovine serum supplier, Fujifilm Irvine Scientific continuously proved its strength in the cell culture solutions space.

Fujifilm Irvine Scientific Celebrates 50 Years of Providing Cell Culture Media Products and Services

Demand for recombinant microorganism-based cell culture supplements is rising on the back of lower contamination risk.

Recombinant Supplements Offer Lower Risk of Cell Culture Contamination

The innovation of single-use technologies is applicable early on in the manufacturing process.

Single-Use Bags Help Maintain Aseptic Ingredient Transfer to Bioreactors

The new facility, which is expected to be operational by spring 2025, will feature 8 x 20,000-L bioreactors with the potential to add further 24 x 20,000-L bioreactors based on market demand.

Fujifilm Chooses North Carolina for New $2-Billion Cell Culture Facility

Using the capabilities of Pharma Waldhof, one of Aceto’s facilities in Düsseldorf, Germany, the company plans to provide customers with access to raw materials, tested products for pharmaceutical cell culture applications, and cell culture media ingredients. 

Manufacturing, Cell Culture and Fermentation