Guidelines for Optimization and Scale-Up in Preparative Chromatography

,
BioPharm International, BioPharm International-01-01-2003, Volume 16, Issue 1

Anurag Rathore, Pharmacia Corporation and Ajoy Velayudhan Optimizing your purification and separation process when your complex biological feedstock is ready for scale-up can be daunting. Your design process can be streamlined, simplified, and made cost efficient if you supplement your empirical approach with the theoretical and experimental tools presented in this article.