Virus Inactivation in the 1990s and into the 21st Century: Part 4, Culture Media, Biotechnology Products, and Vaccines

by Gail Sofer, BioReliance With West Nile virus in the news, viral inactivation is under public scrutiny. Yet, the culture media, the therapeutic product, and the potential viral contaminants can all affect the inactivation method chosen during production. Viral inactivation techniques ? those tried or used in manufacturing or in final biopharmaceuticals, vaccines, and media products ? have been gathered from recent scientific literature and organized in this article series as an addition to your process development toolbox.