A novel coiled flow inversion reactor (CFIR) improves process productivity and performance.
The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platforms.
The authors review the status of expression of antibodies in microbial hosts and present the recent advances in the production of aglycosylated antibodies in bacteria.
The authors review major developments in use of MVDA in bioprocessing applications.
Large-scale implementation of Protein A chromatography offers several challenges.
The authors take a look at the past and future impact of the Indian Pharmacopoeia Commission.
Establishing the CQAs of a mAb product by evaluating impact and uncertainty during risk assessment.
The authors discuss the evolution of the purification platform for manufacturing of mAb therapeutics.
The authors discuss the application of risk management in process lifecycle validation, manufacturing, and change control.
Aggregate formation is influenced by multiple aspects of the bioproduction process but can be mitigated by good process design and control.