Using Amino Acid Analysis to Determine Absorptivity Constants: A Validation Case Study Using Bovine Serum Albumin

John McEntire;John C. Anders;Glenn E. Petrie;Robert L. Marlowe;Benne F. Parten;

Publication

Article

February 15, 2003

BioPharm International

BioPharm International-02-01-2003

Volume16

Issue 2

Using Amino Acid Analysis to Determine Absorptivity Constants: A Validation Case Study Using Bovine Serum Albumin

Author(s):

John McEntire,John C. Anders

by John C. Anders, aaiPharma, Inc., Benne F. Parten, Glenn E. Petrie , Robert L. Marlowe , and John E. McEntire Amino acid analysis (AAA) of well-recovered residues offers an easy way to calculate the absorptivity constant for a known protein. The method provides an absolute measure of protein concentration, free from interference from water, excipients, and bound salts. This article demonstrates a qualified method for determining protein content by AAA.

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Using Amino Acid Analysis to Determine Absorptivity Constants: A Validation Case Study Using Bovine Serum Albumin

Guest Editorial: Maybe You Need a Corporate Marriage Counselor

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The Double Helix at 50: A Half Century of Innovation in the Words of Eight Distinguished Scientists

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Using Amino Acid Analysis to Determine Absorptivity Constants: A Validation Case Study Using Bovine Serum Albumin

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