|Articles|October 27, 2020
Upstream Process Development with a kʟa Criterion
Author(s)Distek, Inc
It can be challenging to define suitable operational definitions for volume-dependent parameters for upstream bioprocesses. In this work, we perform robust DoE mass-transfer characterization of the BIOne SUB and utilize a kʟa criterion to successfully define such parameters for a HEK-293 process.
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