Eppendorf

Articles

A Beginner’s Guide to CHO Culture: Bioprocess Modes – Batch, Fed-Batch, and Perfusion

This application note provides an in-depth look at the batch, fed-batch, and perfusion bioreactor operation modes using the commonly employed CHO cell line as an example.

Bioprocess Knowledge Hub

Whether you are new or experienced in bioprocessing, this website arms you with useful knowledge from general bioprocessing topics to expert advice.

Bioprocessing Basics

This ebook gives an overview of the key characteristics of a stirred-tank bioreactor, its different operation modes, as well as the possibilities of scale-up and tech transfer.

Increasing the Reproducibility of Cell Culture Bioprocesses (July 2024)

This ebook discusses how bioreactors and their components can be employed in cell culture with the goal of increasing process reproducibility.

T Cell expansion in the DASbox® Mini Bioreactor System

This application note examines the suitability of BioBLU® 0.3c Single-Use Bioreactors and the DASbox Mini Bioreactor System in the long-term expansion of CD4+ T cells.

Guide to CHO Cell Bioprocessing

You would like to cultivate your cells in a bioreactor but are unsure how to get started? We guide you through a complete bioprocess from inoculum preparation to sample analysis.

Perfusion bioprocessing at small scale using ATF

We describe the setup of a small scale perfusion bioprocess using a DASbox® Mini Bioreactor System. The system was suitable for the prolonged cultivation of CHO and HEK293 cells.

T Cell Expansion in Small Scale Bioreactors

We tested the suitability of DASbox® Mini Bioreactor System in the long-term expansion of CD4+ T cells as well as the impact of different oxygen tensions on cell proliferation.

E. coli Plasmid DNA Production in Small Bioreactor

In the biopharmaceutical industry, upstream processing for plasmid DNA production is usually optimized at small scale. We demonstrate the feasibility of using the DASbox® Mini Bioreactor System for process development.