Freezing Bulk-Scale Biopharmaceuticals Using Common Techniques ? and the Magnitude of Freeze-Concentration

Aimee C. Kincaid;Timothy G. Hughes;Serena Donnelly Webb;Jonathan N. Webb;David F. Sesin;

Publication

Article

May 15, 2002

BioPharm International

BioPharm International-05-01-2002

Volume15

Issue 5

Freezing Bulk-Scale Biopharmaceuticals Using Common Techniques ? and the Magnitude of Freeze-Concentration

Author(s):

Aimee C. Kincaid,Timothy G. Hughes

by Serena Donnelly Webb, David F. Sesin, Aimee C. Kincaid, Jonathan N. Webb, and Timothy G. Hughes, Integrated Biosystems, Inc. Large-scale freezing and thawing is commonly used in biopharmaceutical manufacturing but is not well understood. Freeze-thaw variations can exist within or between batches, and nonuniform processes raise serious validation concerns.

To view a PDF of this article from the BioPharm International archives, click this link

Articles in this issue

Info+

Analytical Advances: Strategies in Clarifying Mammalian Cultures

Analytical Advances: Using Image Informatics - Focusing Proteomics

The Not-So-Sure Thing

Washington Report: Vaccine Shortages put Spotlight on Production

Outsourcing Outlook: E-Procurement ? Successfully Using and Managing Reverse Auctions

Stay at the forefront of biopharmaceutical innovation—subscribe to BioPharm International for expert insights on drug development, manufacturing, compliance, and more.

Subscribe Now!