Wyatt Technology

SEC-MALS quantifies biophysical attributes of mRNA including molar mass, percent aggregates, Rg and Rh, and how they are affected by formulation and storage conditions.

Measurement of the diffusion interaction parameter versus temperature by dynamic and static light scattering provides comprehensive analysis of protein stability.

Screening studies of candidate proteins are critical in biopharmaceutical discovery. Preliminary assessment of the quality of the protein solutions by dynamic light scattering is imperative for reliable binding results.

By measuring fundamental biophysical attributes, light scattering aids in vaccine discovery, development, and manufacture. This paper covers light-scattering characterization of vaccine classes spanning a large range of physicochemical properties.