The Importance of Freezing on Lyophilization Cycle Development

Thomas W. Patapoff;David E. Overcashier;

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Article

March 15, 2002

BioPharm International

BioPharm International-03-15-2002

Volume15

Issue 3

The Importance of Freezing on Lyophilization Cycle Development

Author(s):

Thomas W. Patapoff,David E. Overcashier

by Thomas W. Patapoff and David E. Overcashier Genentech, Inc. The freezing method used during lyophilization can substantially affect the structure of the ice formed, the water-vapor flow during primary drying, and the quality of the final product. Controlling how a solution freezes can shorten lyophilization cycles and produce more stable formations.

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Guest Editorial: Warning Letters ? A Symptom?

The Importance of Freezing on Lyophilization Cycle Development

Outsourcing Outlook: Using Earned-Value Analysis for Better Project Management

Business Benefits of Computer Systems Validation

Validation of Quantitative PCR Assays?Addressing Virus Contamination Concerns

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The Importance of Freezing on Lyophilization Cycle Development

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