The Importance of Freezing on Lyophilization Cycle Development

Thomas W. Patapoff;David E. Overcashier;

The Importance of Freezing on Lyophilization Cycle Development

March 15, 2002

By Thomas W. Patapoff
David E. Overcashier

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Article

BioPharm InternationalBioPharm International-03-15-2002

Volume 15

Issue 3

by Thomas W. Patapoff and David E. Overcashier Genentech, Inc. The freezing method used during lyophilization can substantially affect the structure of the ice formed, the water-vapor flow during primary drying, and the quality of the final product. Controlling how a solution freezes can shorten lyophilization cycles and produce more stable formations.

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Articles in this issue

Inside Washington: Biotech Manufacturing ? Obstacle or Opportunity?

Guest Editorial: Warning Letters ? A Symptom?

The Importance of Freezing on Lyophilization Cycle Development

Outsourcing Outlook: Using Earned-Value Analysis for Better Project Management

Business Benefits of Computer Systems Validation

Validation of Quantitative PCR Assays?Addressing Virus Contamination Concerns

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The Importance of Freezing on Lyophilization Cycle Development

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