See What Your Chromatography Has Been Missing With MaxPeak High Performance Surface Technologies

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Webinar Date/Time: Tue, Feb 13, 2024 11:00 AM EST

When tackling non-specific adsorption in high-impact chromatographic applications, surface technology can be one’s greatest asset or one’s enemy. Explore the challenges stemming from non-specific adsorption, see where conventional liquid chromatography (LC) surfaces fall short, and learn how disruptive surface modification technology is changing the industry, allowing teams to see what they’ve been missing.

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Event Overview:

This webinar addresses the challenge of non-specific adsorption in liquid chromatography, arising from the interactions of analytes with metal surfaces in LC instruments and columns. These issues, including peak tailing and loss of analyte signals, result from the adsorption of analytes on the metal oxide layer of the components. To combat this issue, Waters developed MaxPeak HPS, a disruptive surface modification technology applied to metal components in HPLC and UPLC instruments and columns.

The hybrid organic−inorganic surface, based on ethylene-bridged siloxane chemistry, significantly improves performance in reversed-phase and hydrophilic interaction (HILIC) chromatography, demonstrating enhanced separations for various small molecules as well as nucleotides, phosphopeptides, and oligonucleotides. The technology proves particularly advantageous in UHPLC/mass spectrometry investigations of metal-sensitive analytes, enabling higher efficiency and improved peak characteristics. This webinar provides background education on non-specific adsorption and its deleterious effects, introduces MaxPeak HPS surface technology and the family of products that leverage MaxPeak HPS technology.

Key Learning Objectives:

  • Examine the challenges caused by non-specific adsorption, and where conventional LC surface technologies fall short.
  • Learn how MaxPeak HPS Technology improves performance in reversed-phase and HILIC chromatography by preventing non-specific adsorption, leveraging disruptive organosilane surface modification technology.
  • Explore the range of LC instruments and columns that leverage MaxPeak HPS, and explore the spectrum of applications.
  • See where surface technology is headed – how seemingly complex tech adapts for the simplicity of routine analysis.


Jim Karafilidis
Principal Product Marketing Manager
Waters Corporation

Jim Karafilidis is Principal Product Marketing Manager for Waters Corporation, where he has worked for 7 years in the LC systems group. He is responsible for Performance LC Systems, which includes ACQUITY Premier, ACQUITY UPLC H-Class PLUS, and ACQUITY UPLC I-Class PLUS systems.

Kim Haynes
Director, Product Marketing & Product Management
Waters Corporation

Kim Haynes is Director of Chemistry Marketing and Product Management in the consumables and lab automation group at Waters Corporation. During her 23 years at Waters, Kim has focused on helping scientists and colleagues understand chromatographic separations and sample preparation. Kim helped launch MaxPeak™ High Performance Surface Technologies in 2020 to help mitigate analyte losses due to non-specific adsorption.

Paula Hong
Senior Manager, Research Support
Waters Corporation

Paula Hong is a Senior Manager in the QAQC business unit at Waters Corporation. She received her B.S. in Chemistry from Bucknell University (Lewisburg, PA) and her Ph.D. in Inorganic Chemistry from The University of Pennsylvania (Philadelphia, PA). Paula has over 17 years’ experience in LC and LC/MS applications and analytical chemistry. She began her career at Waters in the chemistry division, focusing on novel column chemistries for biopharmaceutical applications, and moved to instrument development over 12 years ago. During the past 12 years, Paula has focused on instrument development and understanding the impact of instrument characteristics on method migration and method transfer. She currently manages a team of scientists who support research and development of Waters chromatographic systems.

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