BIO 2010 Exhibitor Showcase

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Amino Acid Analyzers
The Biochrom 30+ Series of amino acid analyzers are based on ion exchange chromatography with post-column derivatization of samples using ninhydrin. These instruments accurately identify and quantify free amino acids and the amino acid composition of proteins and peptides. The instrument is PC-operated, with the user-friendly software controlling all functions, from the autosampler to the analysis and export of data. Advanced fluidics and robust hardware mean easy maintenance for users, backed by Biochrom's service and support team. Biochrom, +44 0 1223 423723,

Besides precision and accuracy, ergonomic handling is particularly important when pipetting. With electronic piston stroke, low weight, and intuitive user guidance, electronic pipettes like the Eppendorf Xplorer minimize user strain. The balance and the finger rest cause a position that is particularly easy on the joints. The basic functions can be selected using a selection wheel. When developing the Xplorer, Eppendorf focused on users who need to perform complex or long pipetting processes, without getting the many different volumes or individual steps confused. Eppendorf AG, +49 40 538 01 640,

Microbial Fermenters
New Brunswick Scientific manufactures advanced microbial fermenters in 1–3,000 L capacities, ideal for R&D through production-scale protein production, biofuels, and vaccines. Recent additions to the line include the new BioFlo 610 Mobile Pilot Plant Fermenter that is compact and versatile. The modular system comes with built-in load cells, choice of 65 or 125 L sterilizable-in-place vessels, and is offered with a comprehensive list of off-the-shelf options facilitating rapid delivery and customization pre- or post-delivery. The mobile skid fits through most doorways, making it easy to move between laboratories in research, pilot plant, and cGMP environments. New Brunswick Scientific, 732.287.1200,

Immobilized Carbon Depth Filters
Pall Corporation's Supra AKS depth filters cartridges fill a gap in sizes between the small 26 cm² Supracap 60 capsules, and the larger-scale Supradisc I modules, all in the Pall line of depth filters featuring Seitz AKS immobilized activated carbon depth filter media. Mid-scale Supra AKS cartridges are ideal for confirmation of results seen at smaller scales, and are appropriate for process scales from 6 to 100+ L. The mid-range Supra AKS depth filters are available in standard 10-, 20-, and 30-inch sanitary-style cartridge sizes. The design ensures tolerance of up to 80 °C at 35 psi (2.4 bar) differential pressure. Pall Life Sciences, 800.717.7255,

BIO Booth #2351
Development Services
Vetter Development Service (VDS) provides support for drug-development projects, from inception to market launch and beyond. Our services include clinical manufacturing at our facilities in Chicago and Ravensburg, with scale-up and transfer to our commercial manufacturing facilities. Thanks to the latest technology and innovative processes, we help you achieve better API yield. VDS provides primary and secondary packaging development, process development, clinical manufacturing, pharmaceutical analysis and stability storage, and regulatory affairs services. Vetter Pharma International GmbH, +49 751 3700 0,


Biological Buffers and Reagents
J.T.Baker biological buffers are nontoxic to cells, are not absorbed through cell membranes, and feature pKa values at or near physiological pH to help stabilize the product as it goes through the many steps required in the purification process. These buffers are part of the Ultrapure Bioreagent family and are characterized by high assay, low insolubles and heavy metals, and the absence of DNase, RNase, and Protease. Mallinckrodt Baker, 800.582.2537,

BIO Booth #1416
cGMP Manufacturing and Lyophilization Services
Therapure Biopharma is a fully integrated biologics contract manufacturer offering a wide range of services including: cell line development, cell banking, analytical development and validation, upstream and downstream process development, process scale-up, clinical- and commercial-scale manufacturing, aseptic fill and finish, and lyophilization. The fill and finish capabilities can accommodate up to 200-mL fills in vials, syringe fills, and IV bags up to 1,000 mL. Therapure also operates two separate cGMP lyophilization suites. The development-scale 1.1 square meter unit is capable of handling up to 4,000 vials per batch. The 7.5 square meter commercial scale unit is capable of up to 32,400 units per batch. Therapure Biopharma, 905.570.8653,

BIO Booth #2463
Disposable Depth Filtration System

The Zeta Plus Encapsulated System is a disposable depth filtration system designed for the bioprocessing industry where upstream cell culture clarification or downstream impurity removal is required. It consists of two product lines: a small system for scale-up studies, and a large system designed for production-scale biomanufacturing. The Zeta Plus Encapsulated System features an ergonomically designed large holder that can be pivoted between horizontal and vertical position. 3M Purification Inc., 203.238.8860,

BIO Booth #5431
Capsule Filters

UltraCap HD (heavy duty) single-use high capacity capsule filter provides high flow rates and high throughput, in lengths up to 40 inches for large volume filtration. The UltraCap HD resists damage caused by rough handling conditions and demanding environments. It has no sharp edges, so it can be integrated into single-use systems. The UltraCap HD is optimized for continuous and batch processing in biomanufacturing operations, and for final and prefiltration in pharmaceutical applications. Offered with T-style sanitary flange inlet and outlet connections, UltraCap HD can be specified with a choice of filter media removal ratings from 0.04 μm to 99 μm. UltraCap HD is available gamma-irradiated for aseptic applications. Meissner Filtration Products, Inc., 805.388.9911,

Single-Use Biomanufacturing System
Sartorius Stedim Biotech's FlexAct enables biomanufacturers to use integrated single-use equipment for all biomanufacturing steps in upstream and downstream processing. FlexAct helps in designing flexible production processes by using out-of-the-box disposable unit operations. FlexAct BP is designed for the preparation of buffers that are essential for stabilizing target molecules and providing for their optimal production conditions. The FlexAct BP system is based on a multifunctional central operating module, which accommodates preconfigured single-use assemblies and a pump and a control unit. FlexAct BP addresses production capacity needs from 50 to 1,000 L for buffer preparation. Sartorius Stedim Biotech, 800.368.7178,