
- BioPharm International-04-01-2014
- Volume 27
- Issue 4
Aggregation System Improves Analysis of Sub-Visible Particles
Aggregation System Improves Analysis of Sub-Visible Particles
Shimadzu introduces the Aggregates Sizer Aggregation Analysis System, which provides real-time quantitative evaluation of 100 nm to 10 μm sub-visible particle (SVP) aggregates. By screening and identifying aggregation-prone proteins in early-stage drug development, manufacturers can save time and reduce costs.
The Aggregates Sizer is capable of identifying all ranges of SVP particles from invisible to visible, in a single measurement in micro-sample quantities as small as 0.4 mL. It also enables quantitative evaluation of the concentration of those aggregates.
In addition, the Aggregates Sizer can execute ongoing measurements in intervals as short as one second, allowing users to evaluate rates of change at intermediate stages during the manufacturing process. A batch cell (5 mL sample capacity) enables observation of aggregation processes as samples are mechanically stimulated. This helps prevent the formation of aggregates during drug manufacturing and improves testing without the need for additional equipment.
Articles in this issue
over 11 years ago
Line of Environmental Measurement Productsover 11 years ago
UPLC Separation Intergrates into Mass Spectrometersover 11 years ago
FDA and Manufacturers Seek a More Secure Drug Supply Chainover 11 years ago
High-Performance Separation-Electrospray Ionization Systemover 11 years ago
Biotech IPOs on a Hot Streakover 11 years ago
Global Instability Affects the Pharma Market in Brazilover 11 years ago
Raw Material Variabilityover 11 years ago
Monoclonal Antibodies Key to Unlocking the Biosimilars Marketover 11 years ago
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