Actavis Unveils Long-Term Growth Strategy
Following its recent acquisition, Actavis (formerly Watson Pharmaceuticals) unveiled its long-term growth strategy during its investor meeting in New York.
Actavis unveiled its long-term growth strategy this week and officially re-introduced itself under the Actavis name following the EUR 4.25-billion ($5.4 billion) acquisition of the Actavis Group by Watson Pharmaceuticals in 2012. Following the completion of its acquisition of the Actavis Group in October 2012, Watson announced the newly combined company would take the Actavis name. At an investor meeting in New York last week, Actavis provided an in-depth look into the newly combined company’s global commercial operations, diversified business structure, and outlook for continued long-term growth.
“2012 was a landmark year for our company as we continued our evolution into a global specialty pharmaceutical leader,” said Paul Bisaro, President and CEO of Actavis, in a Jan. 25, 2013, press release. “Total revenue grew at approximately 29%, non-GAAP earnings per share grew an exceptional 25% and cash flow from operations was in excess of $600 million. We enter 2013 as the world’s third largest global generic company, with a strong, sustainable financial foundation that is well-positioned for continued long-term growth. With a strengthened global commercial position spanning 62 countries and a commitment to funding R&D at levels sufficient to generate a robust and diversified development pipeline encompassing generics, brands and biosimilars, the new Actavis is positioned to deliver on our promise of double-digit growth in 2013 and beyond.”
On a combined basis for Watson and Actavis for 2012, US growth was driven by strong performance of the base business, which was complemented by more than 30 new product launches in the US. In Europe, revenues grew more than 20% from 2011 to 2012. Actavis Specialty Brands, the new name for Actavis’s global brands business, saw growth in select franchises (Rapaflo, Generess, FE, and Crinone), the successful conversion of Androderm 2.5 and 5 mg to 2.0-mg and 4-mg strengths, and continued progress on biosimilars, including the development of rFSH and the Amgen collaboration products. Actavis also advanced its position in women’s health through its recently announced acquisition of Uteron Pharma.
Actavis nows operates 30 facilities representing a combined manufacturing capacity of approximately 44 billion units, with enhanced capabilities in modified-release solid dosage, semisolids, transdermals, liquids, and injectables, according to the company. The company also reported progress on several recent initiatives to rationalize its supply chain, including expected plant closures, sales, or restructuring efforts at its locations in Corona, California; Mississauga, Ontario, Canada; and Alathur, India. Also, in 2012, Actavis opened a new distribution facility in Olive Branch, Mississippi, to improve distribution efficiency.
See related article:
Watson Completes Acquisition of Actavis, Will Take Actavis Name
Harnessing mRNA as a Readout to Develop Robust BioPotency Assays
December 12th 2024Transcriptional activity within a cell can be used to evaluate cell response to a ligand or promoter activity within a transgene or plasmid within a cell. Catalent has developed a relative potency bioassay using real-time quantitative reverse transcription (RT-qPCR) in a duplex format to assess relative transcription activity in cells treated with ligands or transgenic vectors. The assay utilizes two fluorescent dyes with minimally overlapping emission spectra that allow real-time monitoring of the gene expression of both target and normalizer genes. The assay does not require purification of the mRNA produced by the cells once lysis has occurred. Normalizing the qPCR cycle thresholds (CT) of the target transcript to the reference transcript allows response curve to be generated and compared to a reference standard. The generation of a four-parameter fit curve analysis from raw qPCR cycle threshold data allows for comparison of relative potency and assessment of suitability based on curve parallelism. The assay platform has been used by Catalent to qualify a repeatable, accurate, linear, and specific bioassay for assessing relative potency.
The Solution Lies with SOLBIOTE™: Achieving Sustainability, a Growing Focus in Biopharma
October 28th 2024The nexus between biopharmaceuticals and sustainability is seemingly far apart, however, it is increasingly recognized as an inevitable challenge. It is encouraged to take a sustainable approach to reducing the environmental impact of the production and supply of medicines while improving people's health; delivering the well-being of people and the planet. Yosuke Shimojo (Technical Value Support Section Manager, Nagase Viita) will unveil how SOLBIOTE™, a portfolio of injectable-grade saccharide excipients, would be a key for the biopharmaceutical development and achieving sustainability for a better future of the industry.
Exploring New and Improved Analytical Methods for Traditional and Unique Modalities
December 12th 2024Biophysical characterization is critical to understand the make-up and behaviors of biologic therapies and vaccines, both early in development and throughout the manufacturing scale-up process. As biologics become more complex in structure, and as scientists improve their understanding of the effects of structure on stability, efficacy, safety, etc., there is a need to develop new and improved analytical methods to characterize biologic products. During this presentation, experts will discuss the latest challenges in biophysical characterization and will present solutions to overcome these challenges.
