Tosoh Bioscience LLC

Articles

Characterization of Biomacromolecules by FPLC-MALS v2

The coupling of FPLC to MALS not only detects but also quantitatively determines the absolute molecular weight and size of each species, including the targeted molecules, impurities, and its aggregates.

Characterization of Biomacromolecules by FPLC-MALS

The coupling of FPLC to MALS not only detects but also quantitatively determines the absolute molecular weight and size of each species, including the targeted molecules, impurities, and its aggregates.

Tosoh 2 Step mAb Purification Platform

Combining high performance protein A capturing and a single polishing step on a salt-tolerant anion exchange resin, downstream costs were reduced by 45% in this Tosoh 2-step process for mAb purification.

Capture of a scFv from E.coli 

Method for capture of scFV and post-capture-washing condition with chaotropic agents is described. The post-capture washing condition significantly improved HCP removal to increase scFV purity.

Protein A Resin to Reduce Production Cost

This report details how using high capacity TOYOPEARL AF-rProtein A HC-650F resin will reduce production costs, on a per-gram produced basis.

FcR Affinity Chromatography of a Therapeutic Antibody

This application note demonstrates that the TSKgel® FcR-IIIA-NPR affinity column provides fast assessment of biologic activity and glycoform patterns of antibodies.

FcR Affinity Chromatography of a Therapeutic Antibody

This application note demonstrates that the TSKgel FcR-IIIA-NPR affinity column provides fast assessment of biologic activity and glycoform patterns of antibodies.