BioPharm International-11-02-2011

Industry experts from GE Healthcare, Tarpon Biosystems, Polybatics, Merck Millipore, and Repligen discuss the challenges of adapting disposable technology to the chromatography process.

The authors compare the environmental impact of monoclonal antibody production using fixed-in-place processing and single-use systems.

An overview of applications for disposable components and important property considerations.

With careful analysis to mitigate risk, disposable technology and process closure can enable adaptable designs and reduced costs.

Features

November 02, 2011

New technology is designed to improve production efficiency by taking advantage of the properties of single-use bags.

Single-use manufacturing may seem like a new trend, but it has actually been around for almost 30 years, beginning in the early 1980s when filter manufacturers began to make small process-scale plastic filter capsules to replace "junior" size stainless-filter housing assemblies.

Single-Use Technologies and Facilities