BioPharm International-06-02-2010

Advances in Fermentation & Cell Culture: The Keys to Upstream Productivity

An exponential feeding strategy coupled with automation doubled protein yields while reducing fermentation time by 25%.

Two case studies show how advanced information technologies make process development more efficient.

Wet testing of microbial fermenters allows for a greater understanding of the equipment's capabilities.

The quest for increased productivity and better process control combined with patient safety has encouraged biopharmaceutical companies to use chemically defined media for cell culture.

Plant-derived hydrolysates can be used as valuable and practical tools to improve cell culture performance.