Retrovirus and Parvovirus Clearance from an Affinity Column Product Using Adsorptive Depth Filtration

William Larsen;Jeri Ann Boose;Joanne Beck;Barbara Tipton;Thomas O'Brien;

Publication

Article

September 15, 2002

BioPharm International

BioPharm International-09-01-2002

Volume15

Issue 9

Retrovirus and Parvovirus Clearance from an Affinity Column Product Using Adsorptive Depth Filtration

Author(s):

William Larsen,Jeri Ann Boose

by Barbara Tipton, Jeri Ann Boose, Joanne Beck, Thomas O'Brien, and William Larsen, CUNO Incorporated Two types of depth filters are studied for their ability to rid protein solutions of retroviruses and parvoviruses. Such filters are relatively economical and easy to use, so as secondary virus-removing devices, they are beneficial for downstream processing of mammalian cell cultures. Results indicate that depth filters are more effective on retroviruses than parvoviruses.

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Articles in this issue

Retrovirus and Parvovirus Clearance from an Affinity Column Product Using Adsorptive Depth Filtration

Reexamining the Set It and Forget It Approach

Controlled Clean Environment Enclosures: A Cost-Effective Alternative to Cleanrooms

Security in the Corporate Homeland

Integrating New Technology into Blood Plasma Fractionation

Attack Mounts on Pharmaceutical Prices

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