Purification in Batch and Continuous Modes

With BioSC Lab low-pressure chromatography equipment from Novasep, scientists can turn traditional batch chromatography processes into continuous ones as early as the R&D stage. The system can purify a few grams of proteins per day either in continuous, batch or even parallel batch modes.

The simulation software BioSC Predict allows the process developer to set the most efficient mode and parameters to purify biomolecules such as monoclonal antibodies (mAbs), blood factors, and other proteins and switch from batch to continuous mode.

The system can handle from 1 to 6 columns in batch, parallel batch, continuous chromatography or continuous process. Resin and buffer use can be reduced by up to 75%, the company reports.

Source: Novasep