Podcast: Sutro Biopharma and Cell-Free Protein Expression Systems

November 18, 2011

BioPharm International interviews Trevor Hallam, chief scientific officer at Sutro Biopharma. Posted Nov. 2011.

In this first of three podcast interviews, Dr. Hallam, chief scientific officer at Sutro Biopharma, introduces a non-traditional approach for expressing therapeutic proteins and peptides. More specifically, Sutro has developed a proprietary technology for manufacturing proteins in a cell-free system. The system uses a cell extract that contains the necessary machinery for producing protein without the need to maintain cell viability. Essentially, the bioreactor is the cell membrane for a giant cytosolic preparation. Dr. Hallam talks about the advantages of the system and even speculates as to future applications, for example, in a biodefense scenario. Posted Nov. 2011.