Column Packing for Process-Scale Chromatography: Guidelines for Reproducibility

Publication

Article

July 15, 2003

BioPharm International

BioPharm International-07-15-2003

Volume2003 Supplement

Issue 2

Column Packing for Process-Scale Chromatography: Guidelines for Reproducibility

For maximum efficiency, high product yield, and purity, you must produce a homogeneous packed bed every time you perform a separation. Irregularities in packing cause uneven flow within the bed, resulting in band broadening, zone mixing, changes in flow rate, and subsequent loss of product yield and quality. Here we provide guidelines for reproducible column packing along with useful troubleshooting tips.

To view a PDF of this article from the BioPharm International archives, click this link

Articles in this issue

The Basics of Chromatography

Glossary

Choosing the Right Equipment for Process Chromatography

Column Packing for Process-Scale Chromatography: Guidelines for Reproducibility

Stay at the forefront of biopharmaceutical innovation—subscribe to BioPharm International for expert insights on drug development, manufacturing, compliance, and more.

Subscribe Now!