Retrospective: Separations Technology
The 1988 article identified the major challenges with membrane technology as "considerable fouling from solids in the solution that clog the membrane, molecular weight and pore size specifications that often are inaccurate because of the inexact process of membrane fabrication, and vulnerability of membranes to degradation after repeated sanitization steps" (1). BioPharm International talked to Michiel E. Ultee, chief scientific officer at Laureate Biopharmaceutical Services and a member of Biopharm International's Editorial Advisory Board, about what's changed since the article's publication. 
Read the original article. Read the 25th anniversary 

Throughout BioPharm International's 25th Anniversary Year, 2012, we will be rewinding to articles published in the journal's first volume to see where and how technologies have changed in the past couple of decades as well as what the industry may look forward to.