AstraZeneca announced on Sept. 8, 2015 that it will provide 11.5 million pounds (approximately 1.8 million US dollars) to the University of Manchester’s Centre for Cancer Biomarker Sciences over the next five years for the development of a new bioinformatics system to monitor patients in clinical trials. Specifically, the project will measure trial safety, drug efficacy, biomarkers, and drug distribution data in real time, and will use this information for the creation of visual aids such as graphs. The graphs will provide healthcare providers with new tools to make decisions about cancer medications. The research will be carried out at the clinical trials unit of The Christie NHS Foundation Trust.
In addition to the bioinformatics tool, the grant will allow researchers access to training programs in clinical research and pharmacodynamic/pharmacokinetic modeling and will also allow better interaction between patients and those running the clinical trials. “Patient insight is key to our understanding of new cancer drugs,” commented Andrew Hughes, professor of experimental cancer medicine from the University of Manchester’s Institute of Cancer Sciences, in a press release. “The information we get from patients about their experiences of taking new drugs is key to shaping our risk and benefit assessment.”
Source: AstraZeneca
Mastering Antibody-Drug Conjugates
December 19th 2024In this episode, we explore BIOVECTRA’s capabilities in antibody-drug conjugate (ADC) manufacturing, from complex conjugation chemistry to synthesis of highly potent payloads. We’ll also showcase how BIOVECTRA’s extensive experience in complex chemistries and specialized small molecule manufacturing gives them a unique perspective, strengthening their approach to ADC production and ensuring clients receive custom solutions across all project stages.
Filter Sizing for Process Optimization in Life Sciences Sterile Filtration
April 24th 2025Bench-scale filterability studies play a critical role in optimizing sterile filtration in biopharmaceutical manufacturing. By guiding the selection and sizing of filters, these studies help streamline processes, improve scalability, and reduce costs. Through data-driven case studies, this paper highlights how the strategic use of pre-filters and membrane materials can maximize throughput and minimize filter fouling.
VERAXA and Voyager to Create Combined Business for Advancing Pipeline of Next-Gen Cancer Therapies
April 23rd 2025The proposed business combination would create a publicly traded, clinical-stage biopharmaceutical company that will focus on developing a pipeline of next-generation cancer therapies.