Perfusion-based upstream processing is redefining the production of biopharmaceuticals. By enabling continuous media exchange, perfusion systems maintain high cell density and cell health over longer periods, delivering higher productivity than traditional fed-batch approaches. The result is greater process efficiency, improved scalability, and broader access to affordable therapies. As Biopharma manufacturers face increasing pressure to accelerate timelines and reduce costs, perfusion technology offers a powerful path forward. This executive summary explores practical strategies for implementation, key process control insights, and real-world case studies demonstrating the advantages of perfusion-based production.
