Advanced Instruments

Articles

Validation of ICON™ Automated Cell Counting and Viability Assay

This benchmarking study compares the Advanced Instruments Solentim ICON™ viability assay to the performance of a commercially available cell counter. The results demonstrate lower variation, increased precision, and time savings.

Osmolality monitoring for UF/DF and CEX capture of mAbs from mammalian cell cultures

The goal of this paper is to introduce and support the use of osmolality in the Downstream Ultrafiltration/Diafiltration (UF/DF) process steps in the mAb workflow.

Improving Titer, Quality and Efficiency of AAV Manufacturing and Production by Optimizing Osmolality

Modulating osmolality in the early stages of AAV1 upstream manufacturing, can result in improved outcomes such as overall yield, quality, reduced manufacturing costs and improved efficiencies.