Waters Podcast # 5: Advancing Peptide Mapping with Informatics Support for Multiplexed Peptide Fragmentation Data

January 19, 2010



UPLC, QTof, HDMS, and more: A practical guide to the hottest techniques driving the future of biopharmaceutical science

As firms increasingly invest in biopharmaceutical development, there is a widespread need to educate scientists in new technologies and approaches in this rapidly evolving industry. For maximum effectiveness in drug development, the application of new techniques can save time and development costs. In this podcast series, we’ll provide you with a firm knowledge of the latest technological innovations in LC and LC/MS that have been designed to address and advance the very specific needs of the many applications areas in the biopharmaceutical laboratory.

Through a variety of topics highlighting our latest scientific work, this series will help you gain a better understanding of key bio-focused LC, MS, and software advancements. Learn how these solutions have been adopted by industry leaders around the world and how easy it is to implement the tools that deliver faster, better answers relating to the character and quality of your biopharmaceuticals.

This podcast will discuss the various applications of peptide mapping for biotherapeutic protein characterization, and how recent innovations that can raise the efficiency of a lab tasked with carrying out such analyses. In particular, the combination of a data-independent multiplex fragmentation approach (LCMSE) with the appropriate informatics tools are discussed for streamlining biotherapeutic characterization, and the discovery of host-cell protein contaminants.