Leveraging Data for Predictive & Real-time Bioprocess Performance Improvements

Published on: 


Thu, Sep 8, 2022 11am EST | 8am PST | 4pm BST | 5pm CEST Digitalization & leveraging real-time data are key for biopharma process improvement. Insilico models and soft-sensors boost biopharma performance to unprecedented levels.

Register Free: https://www.biopharminternational.com/bp_w/leveraging-data

Event Overview:

Artificial intelligence (AI) and machine learning approaches employing digital twin models enable exploration of the development and manufacturing design space in biopharmaceutical workflows. Driven by data and AI, the virtual exploration of processes for generating predictive outcomes is possible from cell-line development through scale-up manufacturing. Additionally, use of real-time spectroscopy to control glucose-feeding in mammalian cell culture bioprocess is another data-driven method leading to better performance understanding and improvements. Yokogawa solutions related to these approaches are well aligned with Pharma 4.0 goals, whichwill be detailed in this webinar.

Key Learning Objectives:

  • You do not need to be an expert in deep learning & AI to leverage the benefits for improvement of biopharmaceutical processes
  • Integrated bioreactor hardware & software systems employing spectroscopic real-time PAT data for bioprocess upstream applications can be optimized in only 8 weeks for your specific CHO-cell expression system

Who Should Attend:

  • Managers responsible for driving digitalization improvement actions and plans for biopharma
  • Manufacturing & process development scientific staff in biopharma
  • Biopharma software system engineers
  • Bioprocess improvement engineers and scientists


Brett Lepore
Yokogawa Insilico Biotechnology North America
Yokogawa Electric Corporation

Brett received his bachelor’s degree in biotechnology from the University of Massachusetts Lowell. He has extensive clinical research experience working numerous years as a Research Assistant at Massachusetts General Hospital. He also worked prior as a HealthCare account executive, where the team lead managing the business development. In January 2020 he co-established the US subsidiary of Insilico Biotechnology AG, Insilico Biotechnology Corporation. In November of 2021 he supported the acquisition of Insilico Biotechnology by Yokogawa Electric Corporation. Currently he is the Vice President of Yokogawa Insilico Biotechnology Corporation, where he manages the North American operations, and business development of the Insilico Digital Twin Factory. Outside of work, Brett is an avid golfer and boater. He resides in the Boston area.

Paul E. Cizdziel, Ph.D.
Global Market Development, Bioprocess
Yokogawa Electric Company

With over 35 years in business development and marketing positions, Paul has a long history in the biotechnology sector. His education includes a bachelors degree in biology and MBA from the State University of New York at Buffalo, his home town. Paul completed his Ph.D. at the University of Texas, M.D. Anderson Hospital in Cancer Biology. From there, he has been employed with various global bioscience reagent and instrumentation suppliers such as Life Technologies (now Thermofisher) and Merck Millipore. Paul has also held scientific staff positions at the RIKEN Yokohama Institute and was previously Chief Scientific Officer at DNAform K.K. and Chief Marketing Officer with ReproCell, a Japan-based stem cell company. Paul is currently working with Yokogawa Electric Corporation to assist with global market strategy and help establish USA market infrastructure for roll-out of new bioprocess products and services. He has worked with Yokogawa in his current role for nearly 5 years. Besides work, Paul is the Chairperson for the Society for Scientific Exploration branch in Japan and an amateur astrophotographer. Having worked in Japan for over 20 years, Paul is a permanent resident; he lives in Yokohama with his wife and two college-student adult children.

Register Free: https://www.biopharminternational.com/bp_w/leveraging-data