BioPharm International-08-01-2004

BioPharm International

Editorial—Welcome to Our PMP Series

August 01, 2004

Columns and Departments

17

8

What were you doing on the evening of July 20, 1969? If you are at least a baby boomer, you were probably watching Neil Armstrong take "one small step for man, one giant leap for mankind." Sputnik aside, the birth of that monumental achievement probably began with the same question that sparked so many other great feats: "What if?" Where would civilization be if someone periodically hadn't had the imagination and the courage to ask that question, whether their field of expertise was aeronautical engineering, architecture, or biotechnology?

Outsourcing Report: Contract Players

August 01, 2004

Columns and Departments

17

8

Technology innovations aimed at increasing yields and shortening development times can be very cost-effective, promising to reduce the need for large capital investments while getting the client into the clinic much faster.

Optimization, scale-up, and validation issues in Filtration of Biopharmaceuticals, Part 1

August 01, 2004

Filtration

17

8

Filtration is one of the most commonly used unit operations in biopharmaceutical manufacturing. Available formats include direct or normal flow filtration (NFF) and cross or tangential flow filtration (TFF). These methods are used for sterilization and virus filtration, depth filtration or ultrafiltration, and diafiltration applications. Some common objectives include:

Applications: A Total Water Purification System

August 01, 2004

Columns and Departments

17

8

Although sounding like a singular term, a water purification system actually consists of several key components.