Whitepapers

Mar 01, 2017
Sponsored Content
For analysis of rituximab charge variants, method transfer between the Agilent 1260 Infinity Bio-Inert LC and the Agilent 1260 Infinity II Bio-Inert LC produced equivalent results.
Feb 24, 2017
Sponsored Content
Merger and acquisition (M&A) activity is constantly shaping and reshaping the pharmaceutical and biopharmaceutical industries. While 2016 did not go as expected from an M&A perspective what didn’t happen was every bit as important as what did happen.
Feb 21, 2017
Sponsored Content
ΔG complements other biologic stability determinations by providing quantitative insights into stability and aggregation. Unchained Labs tackles the challenges of ΔG measurements with two platforms, UNcle and HUNK.
Feb 02, 2017
Sponsored Content
Detection and quantification of peptides from transmembrane proteins is important for detection of biomarkers and new protein based drugs. This paper presents a fully automated online digestion and LCMS MRM analysis of two model transmembrane proteins, a method that improves reproducibility and decreases chances of contamination.
Jan 11, 2017
Sponsored Content
This Rotronic application note covers the basics of how to choose the correct number of sensors and where to place them for a proper cGMP mapping study.
Jan 04, 2017
Sponsored Content
This application note demonstrates the analysis of antibody drug conjugates by size exclusion chromatography/mass spectrometry using the Agilent 1260 Infinity II Bio-Inert LC.
Dec 14, 2016
Sponsored Content
A recent report published by the Economist Intelligence Unit, The Changing Biopharma Risk Equation, revealed that biopharma executives were eager to explore new possibilities – from developing novel therapies to expanding in emerging markets. However, they were also concerned about risks, especially regulatory uncertainty. In this Q&A, Heike Michaelis shares her thoughts on the evolving regulatory landscape and what this means for the future of biopharma.
Dec 09, 2016
Sponsored Content
This whitepaper reviews the challenges for developing scale-down models for disposable bioreactors (SUBs). Case studies demonstrating transfer from 2000L stainless steel bioreactor to 2000L SUB is presented and the strategies to assess E&L, bag materials, product quality and glycan profiles are discussed.
Dec 07, 2016
Sponsored Content
This work demonstrates the use of an ACQUITY UPLC Glycoprotein BEH Amide, 300Å, 1.7 µm Column to obtain HILIC separations of glycopeptides that complement the chromatographic information afforded by a reversed-phase separation.
Nov 30, 2016
Sponsored Content
Learn why the Thermo Scientific™ Vanquish™ Flex UHPLC system is used for efficient and reliable peptide mapping experiments.
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