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Automated Data Processing Workflows for Targeted Peptide Mapping Data Analysis and Reporting
Thursday, May 11th, 2023 at 10am EDT | 9am CDT | 3pm BST | 4pm CEST
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Event Overview
Mass spectrometry (MS)-based characterization of therapeutic proteins yields product-specific data that are leveraged throughout development to assist science and risk-based decision-making. MS-based targeted peptide mapping is a foundational technique for biotherapeutic characterization and allows relative quantitation of site-specific post-translational modifications that can be used, for instance, to assess product quality.
Recent advancements such as automated sample preparation and data acquisition have improved the overall efficiency of MS-based peptide mapping methodology. However, analysis review and reporting of the targeted peptide mapping data remains a significant bottleneck. This webinar highlights the development of automated workflows in Genedata Expressionist for targeted analysis and reporting of MS-based peptide mapping data.
The newly developed integration and processing capabilities automate several key data processing steps, which includes retrieval of sample metadata from an independent database, analysis of MS-based peptide mapping data, updates to historical MS data libraries for improved workflow performance, and export of standardized reports for subsequent large-scale data aggregation.
Discover how scientists at Janssen are leveraging customized system integration and data processing to:
Automate targeted MS-based peptide mapping of protein therapeutic samples
Drive workflow processes using sample-specific metadata
Standardize data reporting to enable meaningful data aggregation
Key Learning Objectives
Learn how automated peptide mapping workflows reduce variability and improve confidence in results.
See how sample metadata can be utilized to drive sample-specific data processing and analysis.
Discover how standardized reporting enables meaningful data aggregation.
Who Should Attend
Biopharma analytical scientists, lab heads, and directors who are looking to automate targeted mass spectrometry-based peptide mapping workflows for characterization and quality monitoring of biotherapeutics
Featured Speaker
Michael E. Pettit
Scientist
Janssen Research & Development, Malvern, PA, USA
Michael
E. Pettit
is a Scientist at Janssen Research & Development, based in Malvern, PA, USA. Michael gained a Ph.D. from Baylor University in 2018 and subsequently served as a National Research Council Postdoctoral Research Associate for the National Institute of Standards & Technology from 2018 to 2019. An expert in mass spectrometry-based proteomics, Michael has worked on the MS-based characterization of biotherapeutics at Janssen since 2020. His current research focuses on forced degradation studies, including development of mass spectrometry-based methods and data collection strategies for enhanced characterization of biologically relevant peptides and proteins. Michael has special interests in workflow automation, data-aggregation, and artificial intelligence.
For any technical questions please contact
Nicole Valle
:
nvalle@mjhevents.com
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