Whitepapers

Jul 18, 2018
Sponsored Content
Measurement of the diffusion interaction parameter kD by DLS, combined with temperature ramps, provides comprehensive analysis of protein stability. Multiple formulations and candidates are readily screened in standard well plates.
Jul 18, 2018
Sponsored Content
A purified mAb sample, post-protein A purification step was loaded onto a Ca++Pure-HA column. Using potassium phosphate buffer as a loading buffer and potassium chloride as an elution buffer, the mAb aggregate content was reduced from 6.6% to as low as 1.3%.
Jul 10, 2018
Sponsored Content
Hydrophobic interaction chromatography (HIC) is used for the determination of drug-to-antibody ratio (DAR) of a cysteine-linked antibody drug conjugate (ADC).
Jun 25, 2018
Sponsored Content
This Application Note describes a simple and sensitive method for the quantitative analysis of monoclonal antibodies (mAbs) by SEC.
Jun 25, 2018
Sponsored Content
An HCP analysis workflow using the Agilent AssayMAP Bravo platform for automated sample preparation and the Agilent 6545XT AdvanceBio LC/Q TOF for LC-MS/MS analysis.
Jun 25, 2018
Sponsored Content
Agilent Buffer Advisor software with the Agilent 1260 Infinity Bio-inert Quaternary LC System is ideal for automated protein separation by ionic strength gradients.
Jun 25, 2018
Sponsored Content
A quick QC method to indicate the presence of aggregation is presented in this study using an Agilent Cary 60 UV-Vis spectrophotometer.
Jun 25, 2018
Sponsored Content
An automated process for highly sensitive N-linked glycan analysis using fluorescence and additional identification by mass spectrometric detection.
Jun 25, 2018
Sponsored Content
Demonstrates a streamlined approach for accurate mass measurement in the analytical characterization of intact mAbs using the Agilent AssayMAP Bravo platform.
Jun 25, 2018
Sponsored Content
This Application Note presents an integrated workflow for peptide mapping of a mAb from automated sample preparation to data analysis
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