Upstream Processing

Apr 04, 2016
Microchannels show potential benefits for inertial cell sorting and for introducing genetic material into cells.
Apr 01, 2016
BioPharm International
A modular cell-culture platform demonstrates accelerated process development.
Apr 01, 2016
BioPharm International
The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platforms.
Mar 29, 2016
By BioPharm International Editors
Novo Nordisk broke ground on a facility in Clayton, NC, to manufacture APIs for GLP-1 and insulin medicines.
Mar 02, 2016
BioPharm International
The pharma company revealed in a fourth quarter call that it will improve its cell-culture capabilities by focusing on the use of naïve, highly proliferative cells to manufacture its CAR-T drug candidate.
Mar 01, 2016
BioPharm International
Miniature bioreactors add value by reducing validation efforts.
Mar 01, 2016
BioPharm International
Microbial models offer some exciting production alternatives.
Mar 01, 2016
BioPharm International
Collaborative efforts are underway between suppliers and drug manufacturers to address raw material variability.
Mar 01, 2016
BioPharm International
The necessity to detach cells from a culture substrate during cell harvesting remains one of the most challenging steps in a cell-culture process.
Mar 01, 2016
BioPharm International
The authors describe the ways in which manufacturers can mitigate the risks related to the integrity of recombinant transgenes expressed in CHO cells.
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