Tosoh Bioscience LLC

Dec 01, 2005
By BioPharm International Editors
Volume 18, Issue 12

Company Description

Tosoh Bioscience is a major supplier of liquid chromatography products to the pharmaceutical and biotechnology industries. Our products are used for the analysis, isolation, and purification of proteins, peptides, enzymes, nucleic acids, antibiotics, and small molecules. Established in 1987, Tosoh Bioscience became a wholly-owned subsidiary of Tosoh Corporation in 2000. The strength of Tosoh Bioscience lies in its ability to maintain the responsiveness and flexibility of a small, entrepreneurial company, while drawing upon the long history, technical expertise, and manufacturing capacity of its large, well respected parent company.


Size exclusion, reversed phase, normal phase (hydrophilic interaction), affinity, hydrophobic interaction, and ion exchange


Tosoh Bioscience LLC is located in Montgomeryville, Pennsylvania. Supply chain offices are located in Grove City, Ohio. European operations are in Stuttgart, Germany, with sales offices in the United Kingdom and France.

Major products/services:

Tosoh Bioscience offers a comprehensive line of pre-packed columns and media for all common modes of liquid chromatography.

TSK-GEL is available as bulk polymeric resin or in silica- or polymeric-based pre-packed columns. Columns come in microbore analytical through preparative sizes, with particle sizes of column packings ranging from 2 to 20 µm. TSK-GEL bulk resins are available in 10, 13, and 20 µm particle sizes.

TOYOPEARL chromatography resins are based on a semi-rigid, hydrophilic, macroporous backbone, and are stable over the pH 2-13 range. Particle sizes are 20-50 µm superfine (S) grade for the highest performance, 40-90 µm (M) for economical purification, and 50-150 µm (C) for the largest scale chromatography. Chemistries similar to those of TSK-GEL columns allow seamless scale-up from benchtop to manufacturing suite.

ToyoScreen process development columns are easy-to-use, 1 mL and 5 mL prepacked columns of your favorite Toyopearl hydrophobic interaction, ion exchange, and affinity resins. They can be easily connected to ÄKTA, FPLC, and HPLC systems for performing resin screening, process optimization experiments or microgram purifications.

TSK-GEL, Toyopearl and ToyoScreen are registered trademarks of Tosoh Corporation. äKTA and FPLC are trademarks of Amersham Biosciences Limited.

Responsive technical service available via:

  • Phone, toll-free: 800.366.4875

• Email:

Extensive technical assistance is available with:

  • Applications for method development chemists and engineers
  • Method development and scale-up
  • On-site large column packing
  • Validation and registration for process scale customers
  • Re-engineering for improved process economics

Markets Served:

Tosoh Bioscience serves the pharmaceutical and biotechnology industries in North and South America, Europe, the Middle East, and Africa.

156 Keystone Dr. Montgomeryville, PA 18936







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