Manufacturing Systems, Single-Use

Apr 01, 2008
BioPharm International
By BioPharm International Editors
Disposable technologies that mimic the conventional stainless-steel bioreactor will be most readily adopted
Mar 12, 2008
BioPharm International
By BioPharm International Editors
Saint-Gobain Performance Plastics Corporation (Aurora, OH) has acquired the assets of J & J Scientific Products, Inc. (Tampa, FL), a manufacturer of disposable plastic products for the biopharmaceutical market.
Feb 01, 2008
BioPharm International
By BioPharm International Editors
The use of disposables has changed significantly in the biopharmaceutical industry.
Feb 01, 2008
BioPharm International
Two case studies illustrate a systematic approach.
Jan 09, 2008
BioPharm International
By BioPharm International Editors
The automated NucleoCounter from New Brunswick Scientific use disposable cassettes, pre-filled with propidium iodide for accurately counting cells.
Nov 02, 2007
BioPharm International
Single-use systems reduce maintenance and capital expense by eliminating expensive vessels, valves, and sanitary piping assemblies.
Nov 02, 2007
BioPharm International
Comparison of the integrated assembly purified MGG to the control revealed that the purity if the MGG was very high.
Nov 02, 2007
BioPharm International
Disposables are increasingly being used in the manufacture of biopharmaceuticals. This article describes the design of a fully disposable process for the cGMP manufacture of clinical trial grade plasmid DNA. It addresses the rationale for implementing such a process with respect to the manufacture of patient-specific plasmid DNA vaccines for the treatment of leukemia. The process incorporates a number of disposable technologies, which are simple to use and thus reduce the need for investment in expensive equipment and cleaning validation.
Nov 02, 2007
BioPharm International
One of the challenges of adopting single-use technology is that not all cell lines are compatible with disposable bioreactors.
Nov 02, 2007
BioPharm International
A solution for the problems of a "bag in a can" system would be a fully jacketed and insulated container, similar to a traditional freeze tank.
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