Scale Up

Mar 01, 2009
BioPharm International
Robust packing procedures can improve process performance and increase resin lifetime.
Jan 02, 2009
BioPharm International
With virus-based production, vaccines can be available in 10-12 weeks.
Sep 23, 2008
In biomanufacturing today, there is increasing focus on improving process development. The goal is to accelerate development and reduce costs, without compromising the ability to scale up to a robust commercial process later on.
Sep 01, 2008
BioPharm International
How to implement a risk-based approach to eliminating viruses.
Aug 01, 2008
BioPharm International
A review of some recent contributions in process chromatography.
Jul 01, 2008
BioPharm International
By BioPharm International Editors
Best methods to maximize product yield and membrane lifetime to enhance a tangential flow filtration process.
Jun 02, 2008
BioPharm International
Recombinant protein and plasmid DNA production using microbial expression systems is the cornerstone of many biologics manufacturing processes. HCD methods are commonly used for these processes because of the advantages they provide.
Jun 02, 2008
BioPharm International
Using chemically defined feeds with CHO cell lines not only eliminates the variability associated with using plant hydrolysates, but could also improve the productivity of biopharmaceutical protein manufacture and help move therapeutic proteins into clinical trials more rapidly.
Jun 02, 2008
BioPharm International
Gene fusion tags can improve the yield and solubility of many recombinant proteins. This article discusses the most popular fusion tags and the proteases used to remove them, with special reference to recently introduced technologies.
Jun 02, 2008
BioPharm International
With a variety of recombinant, animal-free, defined protein supplements such as growth factors, transferrin, and albumin entering the market, the biopharmaceutical industry now has innovative and safer alternatives to serum and other animal-derived supplements.
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